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Ionis Pharmaceuticals Value Stock - Dividend - Research Selection

Ionis pharmaceuticals

ISIN: US4622221004 , WKN: A2ACMZ

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Description of the company

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; and Kynamro an oligonucleotide inhibitor for use in patients with homozygous familial hypercholesterolemia to reduce low density lipoprotein-cholesterol, apolipoprotein B, total cholesterol, and non-high density lipoprotein. It is also developing inotersen, an antisense drug Ionis to treat patients with hereditary transthyretin amyloidosis; and volanesorsen, an antisense drug for the treatment of familial chylomicronemia syndrome and familial partial lipodystrophy. In addition, the company is developing drugs for various indications, such as cardiometabolic diseases caused by lipid disorders; cardiovascular disease, clotting disorders, and Alzheimer\'s and Parkinson\'s diseases; and acromegaly, amyotrophic lateral sclerosis, beta-thalassemia, and Huntington\'s disease. Ionis Pharmaceuticals, Inc. has a collaboration agreement with AstraZeneca to discover and develop antisense therapies for treating cardiovascular and metabolic diseases, and cancer; and Biogen Inc. to develop and commercialize therapies for neurological disorders, SMA, and neurodegenerative diseases. The company was formerly known as Isis Pharmaceuticals, Inc. and changed its name to Ionis Pharmaceuticals, Inc. in December 2015. Ionis Pharmaceuticals, Inc. was founded in 1989 and is headquartered in Carlsbad, California.

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NEWS


Ionis (IONS) Price Target Hiked Following Positive Zilganersen Trial Results

2025-10-02
Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) ranks among the best biotech stocks to buy. On September 24, Leerink Partners maintained its Outperform rating on Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) and raised its price target from $63 to $68. The boost comes after topline results for Ionis’ Alexander disease therapy, zilganersen. Using the 10-meter walk test (10MWT), Leerink observed […]

Ionis Pharmaceuticals (IONS) Is Up 5.0% After Positive Phase III Results for Alexander Disease Therapy

2025-09-27
Ionis Pharmaceuticals recently announced positive topline results from the pivotal Phase III trial of zilganersen for Alexander disease, a rare and progressive neurological condition lacking approved disease-modifying therapies; zilganersen showed statistically significant stabilization of gait speed with a favorable safety profile in both children and adults. This marks the first time any investigational treatment has demonstrated disease-modifying benefits for Alexander disease,...

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2025-09-26
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Biogen Provides Regulatory Update on High Dose Regimen of Nusinersen

2025-09-23
CAMBRIDGE, Mass., Sept. 23, 2025 (GLOBE NEWSWIRE) -- Biogen Inc. (Nasdaq: BIIB) today announced that the U.S. Food and Drug Administration (FDA) issued a Complete Response Letter (CRL) for the Company’s supplemental New Drug Application (sNDA) for the high dose regimen of nusinersen for the treatment of spinal muscular atrophy (SMA). The FDA letter requested an update to the technical information be included in the Chemistry Manufacturing and Controls (CMC) module of the sNDA. The letter did not

IONS' Rare Neurological Disease Drug Meets Late-Stage Study Goal

2025-09-23
Ionis' zilganersen hits its phase III goal in Alexander disease, paving the way for a potential FDA filing in early 2026.

Biotech Stocks Rally. 3 Favorite Plays From the Charts.

2025-09-23
Biotech stocks are flashing risk-on. The biotech ETF is making a run toward the very round $100 level and flashed relative strength this week despite broader market softness, an encouraging sign. The SPDR S&P Biotech ETF was trading around $97.70 Tuesday.

FDA clears under-the-skin Keytruda; MBX shares double on study data

2025-09-23
The clearance of Keytruda QLEX follows similar approvals for Bristol Myers and Roche. Elsewhere, MBX’s parathyroidism drug impressed investors and Roche claimed success in a breast cancer study.

Ionis announces positive topline results from pivotal study of zilganersen in Alexander disease

2025-09-22
CARLSBAD, Calif., September 22, 2025--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced positive topline results from the pivotal study of zilganersen in children and adults living with Alexander disease (AxD), a rare, progressive and often fatal neurological condition with no approved disease-modifying treatments. Zilganersen 50 mg demonstrated statistically significant and clinically meaningful stabilization on the primary endpoint of gait speed as assessed by the 10-Meter Walk Test (

Ionis and Sobi’s Tryngolza gains approval in EU for FCS treatment

2025-09-22
Tryngolza is designed to reduce the production of apoC-III, a protein involved in triglyceride metabolism.

TRYNGOLZA® (olezarsen) approved in the European Union for familial chylomicronemia syndrome (FCS)

2025-09-19
CARLSBAD, Calif., September 19, 2025--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and Sobi® today announced that TRYNGOLZA® (olezarsen) has been approved in the European Union (EU) as an adjunct to diet in adult patients for the treatment of genetically confirmed familial chylomicronemia syndrome (FCS). The approval follows the positive opinion of the Committee for Medicinal Products for Human Use.